New paper in JACS!

Congratulations to Bea Jones whose work on light-responsive cubosomes has been published in JACS! We created nanoparticles with an internal, cubic liquid crystal phase, suitable to entrap small molecules. Using UV light, the release of these entrapped molecules could be triggered by squeezing the cubic lattice. These stimuli-responsive release systems may have huge potential as next-generation nanodelivery devices for drugs and catalysts. This work is supported by a joint EPSRC/ Diamond Light Source studentship.

You can read the paper here: Light-Responsive Molecular Release from Cubosomes Using Swell-Squeeze Lattice Control, Beatrice E. Jones, Elaine A. Kelly, Nathan Cowieson, Giorgio Divitini, and Rachel C. Evans*, JACS, 2022.

Caption: Formation and release mechanism in light-responsive cubosomes. Azobenzene surfactants (AzoPS) are combined with a lipid, water and dye, mixed and broken up into a dispersion of particles with internal, cubic liquid crystal phases. On irradiation with UV light, the lattice contracts and squeezes out the entrapped dye particles.  

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